Scandinavian journal of gastroenterology
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Scand. J. Gastroenterol. · Dec 2020
Efficacy and safety of tranexamic acid in acute upper gastrointestinal bleeding: meta-analysis of randomised controlled trials.
Studies evaluating the role of tranexamic acid in acute upper GI bleeding (UGIB) have reported conflicting results. In this systematic review, we have evaluated the efficacy and safety of tranexamic acid in UGIB. ⋯ Tranexamic acid does not improve outcomes in UGIB and may increase the risk of venous thromboembolic events.