Respiratory care
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Randomized Controlled Trial Multicenter Study
Guaifenesin has no effect on sputum volume or sputum properties in adolescents and adults with an acute respiratory tract infection.
Guaifenesin (glyceryl guaiacolate ether [GGE]) has been studied as a cough suppressant and as an expectorant; however, published studies to date have failed to find a consistent benefit. ⋯ The recommended dose of GGE had no measurable effect on sputum volume or properties and is unlikely to be an expectorant or mucolytic when used to treat acute RTI. (ClinicalTrials.gov registration NCT01046136.).