Masui. The Japanese journal of anesthesiology
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Perioperative hemorrhage in patients undergoing surgery is a major cause of morbidity and mortality. DRIHEMATO SYSTEM COAG-1 can detect prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) easily. ⋯ The specificity for lotting abnormality of this monitoring system included the following values; PT = 88%, FIB = 100% and TEG = 67%. This study suggests that this monitoring system may be useful in early diagnosis and treatment of postoperative coagulopathy.
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A case of the foreign body due to coring from the rubbercap of a 50 ml Diprivan vial was reported. Furthermore, how the fragment is made and how to decrease the incidence are discussed. ⋯ However, even if the improvement of the rubber, needles and sticking technique is achieved, the occurrence of coring can not be eliminated completely. The best way to avoid coring will be to furnish "50 ml syringes containing Diprivan" commercially.
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A great deal of new information on alpha 2-adrenoceptor agonists has recently been accumulated in humans; alpha 2-agonists have several beneficial actions in clinical anesthesia including sedative, anxiolytic as well as analgesic effects, improved hemodynamic stability, and etc. In the first part of this review, we summarized the structure, signal transmission and basic pharmacology of alpha 2-adrenoceptor agonists (clonidine and dexamedetomidine), and evaluated their usefulness for premedication, and as anesthetic adjuvants as well as agents for stabilizing circulation in the clinical settings. In addition, we referred to practical problems associated with their use.