Masui. The Japanese journal of anesthesiology
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Thirteen patients were intubated with cuffed reinforced spiral tracheal tubes. Intracuff pressure and volume were measured as the position of the head and neck was altered. No significant changes in intracuff pressure and volume were observed with lateral rotation of the head. ⋯ Reinflated intracuff volume decreased and reinflated intracuff pressure increased significantly, and residual excessive pressure was observed in 4 patients with flexion. Both reinflated intracuff volume and pressure increased significantly, and excessive pressure was observed in 8 patients and residual air-leak developed in a patient in spite of excessive pressure with extension. The authors speculate that endotracheal tube movement by changes in head and neck position has effects on intracuff pressure and volume.
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We investigated the effect of intravenous magnesium, a N-methyl-D-asparate (NMDA) receptor antagonist, in 8 patients suffering from neuropathic pain (post herpetic neuralgia or causalgia etc.). After the nerve block, magnesium sulphate (0.5 mol.l-1) 5 ml was administered intravenously by bolus infusion taking 5 min, followed by continuous infusion of the same dose for one hour. All patients were treated with this therapy once a week. ⋯ Some patients felt heat sensation immediately after the bolus infusion of Mg, and had a good sleep after this therapy. However, there were not any severe side effects and significant change in HR or BP. We conclude that this therapy with magnesium once a week is safe and effective for relieving neuropathic pain.