Acta anaesthesiologica Belgica
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Acta Anaesthesiol Belg · Jan 1977
Total intravenous anesthesia with etomidate. III. Some observations in adults.
An investigation was undertaken to determine the dosage of etomidate required to maintain sleep in adults undergoing surgery under regional local anesthesia. Premedication of diazepam 10 mg and atropine 0.5 mg was given, and sleep was induced and maintained by intermittent intravenous injections of etomidate 0.1/mg/kg, given whenever the patient would open his eyes on request. ⋯ It is considered unlikely that etomidate will prove to be the hypnotic of choice for a totally intravenous anesthetic technique in adults because of the high incidence of myoclonia after prolonged administration. In several patients uncontrollable muscle movements persisted for many minutes after complete recovery of consciousness.
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Acta Anaesthesiol Belg · Jan 1977
Comparative Study Clinical Trial Controlled Clinical TrialEpidural anesthesia for surgery: a comparative double-blind study of etidocaine and bupivacaine.
The author reports the comparative effects of 2 local anesthetic agents injected into the epidural space: 1% etidocaine and 0.5% bupivacaine, both containing epinephrine (5 microgram/ml). Twenty ml of one of these solutions were administered under double-blind conditions to 40 patients undergoing orthopedic, urological, gynecological or general surgery. ⋯ After etidocaine, motor block occurred more often, was more complete and developed more rapidly than after bupivacaine. The incidence of peroperative and postoperative complications was comparable in both groups.