Middle East journal of anaesthesiology
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Middle East J Anaesthesiol · Feb 1991
Randomized Controlled Trial Comparative Study Clinical TrialTracheal soiling with blood during intranasal surgery--comparison of two endotracheal tubes.
Sixty adult patients, ASA Classes I & II, were involved in a study to compare the effectiveness of Mallinckrodt Hi-Lo-Evac tube and Portex blue line tube in preventing soiling of the lower airways during intranasal surgery. The Hi-Lo-Evac tube with and without pack was significantly more effective than the Portex tube with pharyngeal pack (P less than 0.002) and (P less than 0.01 respectively). ⋯ The more effective protection of the lower airways by the Hi-Lo-Evac tube is attributed to the facility of subglottic aspiration during surgery. It is suggested that the Hi-Lo-Evac tube could be used with safety during intranasal surgery in order to reduce postoperative morbidity associated with the use of pharyngeal pack.
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Middle East J Anaesthesiol · Feb 1991
Randomized Controlled Trial Comparative Study Clinical TrialThe hemodynamic effects of intravenous norepinephrine versus epinephrine and phenylephrine in patients with ischemic heart disease.
The hemodynamic effects of an intravenous bolus of norepinephrine 10 micrograms, phenylephrine 100 micrograms and epinephrine 10 micrograms were investigated in 30 patients scheduled for coronary artery bypass grafting. The hemodynamic changes following norepinephrine were similar to those achieved by phenylephrine. ⋯ In contrast, epinephrine increased the mean arterial pressure and cardiac output without a significant change of systemic vascular resistance. The results suggest that intravenous norepinephrine acts similar to phenylephrine as an alpha-adrenergic agonist, while epinephrine acts predominantly as a beta-adrenergic agonist.