Middle East journal of anaesthesiology
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Middle East J Anaesthesiol · Jun 1996
Randomized Controlled Trial Clinical TrialProphylactic administration of ondansetron in emergency intraabdominal operations.
Efficiency of ondansetron, a selective 5-HT3 receptor antagonist, in prevention of postoperative nausea and vomiting in 40 ASA I-II patients who will undergo emergency intraabdominal operations is studied in a randomized double-blind and placebo controlled study. Patients of no premedication are administered 4 mg i.v. ondansetron or placebo (saline) before induction. Thiopental (4 mg/kg) was used for induction, succinylcholine (2 mg/kg) for muscular relaxation, and 50% nitrous oxide in oxygen and isoflurance (0.8-1.5%) for the maintenance of anesthesia, and fentanyl and norcuron were administered when necessary. ⋯ Although is was effective during 2-24 h period, the difference was not statistically significant (p > 0.05). No significant difference was observed between the groups in terms of vital findings, laboratory findings and side effects (p > 0.05). Therefore it is concluded that administration of prophylactic i.v. ondansetron to patients undergoing emergency intraabdominal operations is effective in prevention of nausea and vomiting without any significant side effects.
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Middle East J Anaesthesiol · Jun 1996
Comparative StudySevere neck burns and laryngeal mask airway for frequent general anesthetics.
Securing the airways in a patient suffering severe neck burns or its sequalae may present a challenge to the most experienced anesthesiologist. We investigate the utility of the Laryngeal Mask Airway (LMA) in this situation. We report on success, failure of complications of LMA insertion at the induction of general anesthesia in 23 patients of a Major Burns Unit and compare our results to our records of patients intubated endotracheally in the Unit. 14 out of 15 patients with neck burns had a LMA inserted with no difficulty or complications, while difficult endotracheal intubations in patients with neck burns were more frequent with statistical significance compared to patients with intact necks. LMA insertion seems to ignore the difficulties met with endotracheal intubation in this context.
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Middle East J Anaesthesiol · Jun 1996
Modified Laryngeal Mask Airway--a useful aid to fiberoptic intubation.
Modified Laryngeal Mask (MLMA) aided fiberoptic intubation (FOI) using larger than 6 mm ID endotracheal tube was studied in 25 adult patients and compared to unaided FOI in another 25 patients. MLMA aided FOI was successful in 96% cases compared to 56% in the unaided group. ⋯ However, maximum fluctuations in the heart rate and mean arterial pressure in the immediate post-intubation period were statistically insignificant between the groups. We conclude that MLMA not only adds to success rate of FOI but also significantly reduce the FOI time in adult patients.