Middle East journal of anaesthesiology
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Middle East J Anaesthesiol · Feb 2007
Randomized Controlled Trial Comparative StudyRecovery profile for magnetic resonance imaging in pediatric daycase--sevoflurane vs. isoflurane.
Magnetic resonance imaging (MRI) is gaining ground over other investigations particular in study of brain and soft tissues. The MRI procedure is painless but requires an immobile patient for a successful study. Children are required to be sedated or anesthetized for this procedure. We compared two inhalational anesthetics, namely sevoflurane and isoflurane, for the recovery profile of each with aim to determine the ideal drug for early discharge of children. ⋯ Sevoflurane can be an ideal inhalational anesthetic for Volatile Induction and Maintenance Anesthesia (VIMA) in children under going daycase MRI examinations.
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Middle East J Anaesthesiol · Feb 2007
Randomized Controlled Trial Comparative StudyPost-thoracotomy analgesia--comparison epidural fentanyl to intravenous pethidine.
To evaluate the efficacy of postthoracotomy analgesia with intermittent epidural fentanyl. 50 patients were allocated randomly into 2 groups. The first group received intermittent epidural fentanyl and the second group received intermittent intravenous analgesia using pethidine. The variables studied were: pain score; total amount of additional intravenous opioid analgesia, and ventilatory function parameters [forced vital capacity (FVC), forced expiratory volume in the first second (FEV1) and FEV1/FVC ratio]: ⋯ The analgesic effect of intermittent epidural fentanyl is not adequate and postoperative pain relief has not any significant advantage over the more easily-applied intravenous analgesia. However, better preservation of ventilatory function makes epidural fentanyl a useful adjunct analgesia in reduction of post-thoracotomy pulmonary complications.
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Middle East J Anaesthesiol · Feb 2007
Randomized Controlled TrialThe effect of betamethasone gel in reducing sore throat, cough, and hoarseness after laryngo-tracheal intubation.
Tracheal intubation for general anesthesia often leads to traumatization of the airway mucosa resulting in postoperative sore throat, hoarseness and cough. This study was undertaken to determine the effects of betamethasone gel in reducing these complications. ⋯ Betamethasone gel, when was used for lubrication of endotracheal tubes pre-operatively, was shown to be effective in decreasing postoperative sore throat, hoarseness, and cough.
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Middle East J Anaesthesiol · Feb 2007
Randomized Controlled TrialWomen emerge from general anesthesia faster than men.
Interest in the speed with which patients recover post operatively, the type of deficits that anesthesia may induce in them and the overall profile of their physiologic and psychological states, has grown rapidly over the last two decades. Recovery from general anesthesia is dependent on factors governing drug sensitivity and drug disposition. In our study of 60 males and 60 females we have tried to find out if there is any significant difference in males and females, in their emergence from the effects of general anesthesia. ⋯ Considering the multitude of factors that may influence recovery, the gender effect appears to be a strong one. The difference could probably be explained by differences in physiology, enzyme activity etc. Investigators have noted that normal differences account for changes in function of the GABA receptor known to be important in the action of many anesthetics.
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Middle East J Anaesthesiol · Feb 2007
Randomized Controlled Trial Comparative StudyCombined spinal-epidural analgesia in labor--comparison of sufentanil vs tramadol.
Combined spinal-epidural (CSE) analgesia is becoming increasingly used to provide pain relief during labor. It combines both the rapid onset of the spinal analgesia and the flexibility of the epidural catheter. Intrathecal sufentanil provides rapid-onset and profound analgesia during the first stage of labor. The dose required to produce this effect can be associated with maternal respiratory depression, hypotension, nausea, or pruritus. The major concern of the anesthesiologist is to limit these side effects sources of discomfort to a parturient, by choosing the optimal dose of sufentanil or searching for an alternative. The purpose of this study is to compare tramadol and sufentanil used in CSE analgesia in terms of duration of analgesia and frequency of adverse maternal or fetal effects. ⋯ 2.5 micrograms of intrathecal sufentanil combined with 2.5 mg bupivacaine provides rapid-onset and profound analgesia during the first stage of labor without adverse maternal or fetal effects. 25 mg intrathecal tramadol with 2.5 mg bupivacaine had longer-lasting analgesia. The major side effect was vomiting.