Middle East journal of anaesthesiology
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Sixty consecutive patients who were given an anesthetic, not needing tracheal intubation, received desflurane as part of the anesthetic technique to assess the incidence of upper airway irritation. A variety of induction agents and artificial airways were used. The incidence of upper airway irritation was recorded. ⋯ Six patients who coughed were given no premedication or were anesthetized before it could take effect. Coughing occurs during general anesthesia, but it is caused by many factors. In adults, using desflurane it does not appear to be a significant risk factor.
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Middle East J Anaesthesiol · Oct 1995
Biography Historical ArticleHumphry Davy's small circle of Bristol friends.
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Middle East J Anaesthesiol · Jun 1995
Randomized Controlled Trial Clinical TrialHemodynamic and oxygenation variables during radical cystectomy. Does the anesthetic technique really matter?
The effect of anesthetics on hemodynamic variables (HV) has been clarified, but ambiguity existed concerning their effect on oxygenation variables (OV). Radical cystectomy provided a clinical setting for studying the effect of anesthetics on perioperative HV and OV. Patients subjected to radical cystectomy (n = 33) were assigned through balanced randomization to receive one of four anesthetic modalities, namely; group I: inhalation anesthesia using N2O:O2, halothane, d-tubocurarine (n = 11); group II: inhalation anesthesia using N2O:O2, halothane, d-tubocurarine, and supplemented with epidural analgesia (EA) (n = 11); group III: total intravenous anesthesia (TIVA) using ketamine 10-30 ug.kg-1.min-1, propofol 2 mg.kg-1.h-1, d-tubocurarine, and supplemented with continuous EA (n = 6): and group IV:TIVA using ketamine 20-50 ug.kg-1.min-1, midazolam in increments of 1.5 to 5 mg, and supplemented with intermittent EA (n = 5). ⋯ Mixed venous oxygen tension and saturation were higher in group I over group IV. Other OV did not show remarkable differences. In conclusion, HV and OV in 4 anesthetic modalities did not elicit striking differences.
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Middle East J Anaesthesiol · Feb 1995
Randomized Controlled Trial Comparative Study Clinical TrialEvaluation of different induction techniques for tracheal intubation.
Conditions for tracheal intubation and the hemodynamic changes associated with different intravenous anesthetic induction techniques were studied in seventy-two ASA I patients randomly assigned to one of six groups (G). Anesthesia was induced with I. V. propofol 2.5 in G 1, 3, 5 or with thiopental 5 mg/kg (G2, 4, 6). ⋯ In G 5 and G 6 the "timing principle" was used; atracurium 0.5 mg/kg was given first followed by propofol and thiopental, and one minute after the induction agent intubation attempted. There was no statistically significant difference in the intubating conditions between the six groups of patients studied. Similar to succinylcholine timing technique with atracurium and propofol or thiopental reliably provided excellent or good intubating conditions in two minutes.