Revista española de anestesiología y reanimación
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Rev Esp Anestesiol Reanim · Apr 2000
Randomized Controlled Trial Comparative Study Clinical Trial[Cardiovascular response to tracheal intubation in patients with intracranial tumor. Comparative study between urapidil and lidocaine].
To compare the effects of urapidil and lidocaine on cardiovascular response to laryngoscopy and tracheal intubation in patients with brain tumors. ⋯ In patients undergoing neurosurgery to remove a supratentorial tumor, both lidocaine and urapidil reduce the pressor response to laryngoscopy and tracheal intubation at the doses given in this study. However, neither was able to prevent the increase in heart rate.
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Rev Esp Anestesiol Reanim · Apr 2000
Randomized Controlled Trial Comparative Study Clinical Trial[Ketorolac versus tramadol: comparative study of analgesic efficacy in the postoperative pain in abdominal hysterectomy].
To compare the analgesic efficacy of tramadol to that of ketorolac trometamol administered intravenously and at fixed times over the 24 hours after abdominal hysterectomy. ⋯ During the first 12 hours following surgery, a 100 mg dose of tramadol has been shown to provide more effective pain relief than 30 mg of ketorolac administered intravenously every 6 hours. The only drawback to administering the drug intravenously was the high incidence of postoperative vomiting.
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Rev Esp Anestesiol Reanim · Apr 2000
Randomized Controlled Trial Comparative Study Clinical Trial[Direct effect of anesthetic inducers on the electromyographic signals of the adductor pollicis].
To analyze the effect of thiopental, propofol, etomidate and midazolam on electromyographic study of the adductor pollicis before muscle relaxation. ⋯ Thiopental and etomidate induce slight muscle relaxation at the expense of a reduction in T1 without changing the TOF-ratio, an effect that might be useful for rapid induction. Propofol and midazolam do not affect the electromyogram of the adductor pollicis. Thus, propofol is the anesthetic induction agent of choice for clinical studies on non-depolarizing muscle relaxants given that it changes neither T1 nor the TOF-ratio.
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Meperidine was the first synthetic opioid agent. It acts mainly as an antagonist of mu (#m) receptors and has an analgesic potency ten times greater than that of morphine. Like other opioid drugs, meperidine causes nausea, vomiting, urinary retention and respiratory depression; a point of difference, however, is that it acts on nerve fibers and has properties similar to those of local anesthetics. ⋯ An intravenous route has been used for treating moderate to severe pain, for regional anesthesia, for premedication and for analgesia during anesthesia. Meperidine's action on kappa receptors has meant that it is considered the most effective drug for treating postanesthetic trembling. Although meperidine has been used effectively to treat non-surgical pain, mainly from colic, this review focuses on its usefulness in the perioperative period.