Revista española de anestesiología y reanimación
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Rev Esp Anestesiol Reanim · Nov 2004
Review Multicenter Study Clinical Trial Controlled Clinical Trial[Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides].
To study the incidence of pain upon injection of 1% propofol (Propofol-Lipuro 1%, B. Braun, Melsungen, Germany) in a 10% fat emulsion containing equal proportions (50:50) of medium- and long-chain triglycerides. ⋯ The incidence of pain upon injection of propofol-lipuro is low in comparison with incidence rates reported in the literature for the traditional formula, but administration of the fat emulsion formula through a vein on the dorsal side of the hand or through a venous catheter smaller than 18 G should be avoided. Double-blind randomized controlled trials should be conducted to clarify the advantages that propofol-lipuro seems to offer.