Journal of the Medical Association of Thailand = Chotmaihet thangphaet
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Randomized Controlled Trial Clinical Trial
Analgesic effect of intraperitoneal instillation of bupivacaine for postoperative laparoscopic cholecystectomy.
To study the effectiveness of intraperitoneal instillation of bupivacaine for postoperative laparoscopic cholecystectomy pain relief, especially specific pain (visceral pain, shoulder pain and epigastric pain). ⋯ In this study, intraperitoneal instillation of bupivacaine does not show any advantage for postoperative analgesia after laparoscopic cholecystectomy.
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Comparative Study
Intraocular pressure changes during general anesthesia in children, comparing no mask, undermask and laryngeal mask airway.
In a before and after study of 35 children's eyes, we compared the intraocular pressure (IOP) during general anesthesia consisting of 6-8 per cent sevoflurane in 100 per centoxygen at induction. IOP measurement, blood pressure, oxygen saturation, and heart rate were recorded in patients with an applied face mask while the patient became unconscious and proceeded to surgery. ⋯ The IOP with an applied face-mask was significantly statistically different from that after insertion of a LMA (12.8 +/- 3.1 and 12.0 +/- 3.3, p < 0.05) but not significantly different cilnically. We concluded that clinically, the IOP does not change in children given general anesthesia with a correct size of face mask when compared with insertion of an LMA or no face mask.
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Case Reports
Drug-induced hyperthermia and rhabdomyolysis during the perioperative period: report of three patients.
Drug-induced hyperthermia is one condition that anesthesiologists may meet even though it is uncommon, it is life threatening. We report 3 cases of patients at Siriraj Hospital, Mahidol University who developed drug-induced hyperthermia and rhabdomyolysis from different mechanisms. In two of them, the diagnosis was suspected malignant hyperthermia. ⋯ As a result of early detection and early manangement, these three patients survived without any permanent damage to vital organs. We conclude that Thai anesthesiologists should be more aware and alert to drug-induced hyperthermia especially as nowadays many teenagers abuse stimulant drugs and "triggering" drugs as antidepressant or serotonin reuptake inhibitors are prescribed more frequently. Early detection and management will decrease morbidity and mortality.
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The routine plain-film abdominal series, consisting of supine and upright abdominal radiographs and upright chest radiograph of 246 patients, who presented with abdominal pain from the emergency room of Bangkok Metropolitan Administration Medical College and Vajira Hospital from January 2000 to May 2001 were reviewed. Each radiograph was independently interpreted to detect any radiographic abnormality. ⋯ Most of the detectable abnormalities in the upright views were pneumoperitoneums that were clearly demonstrated on the upright chest radiographs. So elimination of the upright abdominal view from the routine plain-film abdominal series in the screening of surgical cases from medical cases could result in cost-saving and a decrease in radiation exposure without significant loss of diagnostic information.
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Randomized Controlled Trial Clinical Trial
EMLA cream and intraperitoneal lidocaine decrease intraoperative pain during postpartum tubal sterilization.
We conducted a randomized, double blinded, placebo controlled trial to evaluate the effectiveness of EMLA cream together with intraperitoneal lidocaine for pain relief in postpartum tubal ligation. In a factorial designed study, 90 postpartum patients were randomly assigned to have 5 g of EMLA or placebo cream applied to the skin in 2 groups of 45 patients and to have intraperitoneal instillation of 20 ml of either 1 per cent, 2 per cent lidocaine or normal saline in 3 groups of 30 patients. A numerical rating pain score (0-10) was used during skin check, skin infiltration and uterine tube manipulation. The pain scores were significantly lower in the EMLA group as compared with the placebo group during the skin forceps check (p < 0.001) and during local skin infiltration (p < 0.05). The pain scores were also significantly lower during intraabdominal manipulation in the group using either 1 per cent or 2 per cent intraperitoneal lidocaine as compared with the group using normal saline (p < 0.001), but no difference was found between the groups using 1 per cent and 2 per cent lidocaine. ⋯ Five g of EMLA cream applied to the skin together with 20 ml of 1 per cent lidocaine instilled into the abdominal cavity effectively decrease intraoperative pain in patients undergoing postpartum tubal sterilization under local anesthesia.