Journal of the Medical Association of Thailand = Chotmaihet thangphaet
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Gabapentin is an antiepileptic drug. It is structurally similar to yaminobutyric acid (GABA), which crosses the blood-brain barrier. Gabapentin is absorbed into the blood by the L-amino acid transport system. The oral bioavailability of gabapentin displays dose-dependence. Plasma concentrations ofgabapentin are not directly proportional to dose. Therefore, pharmacokinetic of gabapentin is essential for patients who have to receive gabapentin 600 mg. ⋯ The data show the pharmacokinetic parameters of gabapentin 600 mg. These data should be used to support the assignment of therapeutic purposes for patients who have to receive gabapentin 600 mg.
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Randomized Controlled Trial Comparative Study
Agreement and reproducibility of Tono-Pen XL tip covered with ocufilm and fingertip of surgical glove in intra-ocular pressure measurement.
To compare the effect of using the fingertip of a surgical glove over Ocufilm (Reichert Technologies, NY, USA) on the agreement and reproducibility of measuring intra-ocular pressure (IOP) by the Tono-Pen XL (Reichert Technologies, NY USA). ⋯ A significant agreement exists between using Ocufilm and the fingertip of a surgical glove to cover the tip of a Tono-Pen XL for measuring IOP The coefficient of repeatability was comparable between the two different types of tip covers. When measuring IOP the tip of a Tono-Pen XL could therefore be covered by either Ocufilm or the fingertip of a surgical glove without compromising accuracy.
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Comparative Study
Comparison of age-based and height-based formula for tracheal tube size in cardiac children.
To compare the effectiveness of age-based formula (ABF) and height-based formula (HBF) for pediatric cardiac patients, including patients with failure to thrive (FTT). ⋯ Age- and height-based formula for estimating tube size in cardio-surgical children is equivalent and independent of physical development. Age-based formula as the simple method can be recommended. The availability of three tube sizes (one smaller one larger than estimated) should be ensured.
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Anatomical variations of the V2 vertebral artery study by measuring the width of transverse foramen.
To evaluate the incidence of anatomical variations of the V2 segment of the vertebral artery (VA) using dry bones. ⋯ Anatomical variations of the V2 segment of the VA do exist at C4, C5, and C7. The awareness of this abnormality may reduce the risk of catastrophic intraoperative VA injury.