The American review of respiratory disease
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Am. Rev. Respir. Dis. · Sep 1978
Biochemical and physiologic changes in lungs of rats exposed to a cadmium chloride aerosol.
The purpose of this study was to examine the in vivo effects of acute exposure to a cadmium chloride aerosol on the activity of pulmonary enzymes and selected physiologic parameters that are altered by exposure to oxidant agents. Male rats were exposed for 1 hour to 0.5 per cent aerosol of cadmium chloride. ⋯ Light microscopic examination of lung tissue revealed initial pulmonary edema on day 1 that progressed to interstitial pneumonitis on day 5, with some recovery by 11 days after exposure. The cadmium induced biochemical, physiologic, and pathologic alterations were similar to the responses observed in lungs of rats exposed to a wide variety of pulmonary irritants; thus, the changes observed may represent a nonspecific response to tissue injury.
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Am. Rev. Respir. Dis. · Sep 1978
Biography Historical ArticleThe award of the Will Ross Medal for 1978.
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Am. Rev. Respir. Dis. · Sep 1978
Biography Historical ArticleAmerican Lung Association. The award of the Trudeau Medal for 1978 (Theodore L. Badger).