The American review of respiratory disease
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Am. Rev. Respir. Dis. · Mar 1991
Randomized Controlled Trial Clinical TrialPressure-time product during continuous positive airway pressure, pressure support ventilation, and T-piece during weaning from mechanical ventilation.
The objective of this study was to compare the effects of continuous positive airway pressure (CPAP), pressure support ventilation (PS), and T-piece on the pressure-time product (PTP) during weaning from mechanical ventilation. The PTP is an estimate of the metabolic work or oxygen consumption of the respiratory muscles. We studied 10 intubated patients recovering from acute respiratory failure of various etiologies. ⋯ The contribution of the decrease in PEEPi to the reduction in PTP(es) amounted to 36%. With PS-5, respiratory system mechanics and PEEPi were not significantly different compared with T-piece. With CPAP-0, PTP tended to be lower than with T-piece.(ABSTRACT TRUNCATED AT 250 WORDS)