Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
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Comparative Study
[Implementation of POSSUM scoring system in assessing morbidity after laparoscopic colorectal surgery].
The aim of the study was objective morbidity comparison of the open and laparoscopic colorectal surgery using the recalibrated POSSUM scoring system, taking into account potential "case mix" of samples. ⋯ The elective laparoscopic colorectal surgery is associated with lower post-operative morbidity than the open approach, including high-risk patients.
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Intestinal fatty acid binding protein (I-FABP) deriving from the cytoplasm of the intestinal epithelial cells is a new biochemical marker with potential to indicate intestinal mucosal injury early in the phase of enterocyte damage. I-FABP is thought to be promising marker for detection of the systemic inflammatory response syndrome (SIRS) and sepsis before its onset. ⋯ There were no differences in the mean plasma I-FABP levels preoperatively and in the postoperative period after the major surgery. Because surgery alone probably has no influence on I-FABP plasma levels we can say that the concept of l-FABP as the early marker of the intestinal mucosal injury is also viable in postoperative period.