The Lancet. Respiratory medicine
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Randomized Controlled Trial Multicenter Study Comparative Study
Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomised controlled trial.
Previous studies suggested intravenous or nebulised magnesium sulphate (MgSO(4)) might improve respiratory function in patients with acute asthma. We aimed to determine whether intravenous or nebulised MgSO(4) improve symptoms of breathlessness and reduce the need for hospital admission in adults with severe acute asthma. ⋯ UK National Institute for Health Research Health Technology Assessment Programme.
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Randomized Controlled Trial Multicenter Study Comparative Study
Magnesium sulphate in acute severe asthma in children (MAGNETIC): a randomised, placebo-controlled trial.
Little evidence is available for the effect of nebulised magnesium sulphate (MgSO(4)) in acute asthma in children. We assessed the effect of MgSO(4) treatment in children with severe acute asthma. ⋯ National Institute for Health Research Health Technology Assessment Programme.