Journal of anaesthesiology, clinical pharmacology
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J Anaesthesiol Clin Pharmacol · Apr 2011
Postoperative analgesia in children when using clonidine or fentanyl with ropivacaine given caudally.
The aim of the study was to compare the efficacy of clonidine and fentanyl as an additive to ropivacaine given via single shot caudal epidural in pediatric patients for postoperative pain relief. ⋯ The analgesic properties of clonidine and fentanyl as additives to ropivacaine in single shot caudal epidural in children are comparable but clonidine offers a more favorable side effect profile. The use of clonidine as additive to ropivacaine in caudal epidural is superior choice to fentanyl because of lack of unwanted side effects and increased patient comfort.
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J Anaesthesiol Clin Pharmacol · Jan 2011
Comparative evaluation of ketamine - propofol, fentanyl - propofol and butorphanol-propofol on haemodynamics and laryngeal mask airway insertion conditions.
Laryngeal mask airway is a non invasive supraglottic device which has led to a radical change in the management of modern general anaesthesia. Propofol as a single agent is unsatisfactory and to overcome problems associated with LMA insertions. In the present study, we evaluated the haemodynamic changes and laryngeal mask airway insertion conditions comparing ketamine and opioids as adjuncts to propofol. ⋯ It is concluded that addition of butorphanol to propofol for LMA insertion provided absolute jaw relaxation and excellent insertion conditions with stable haemodynamics Side effects like coughing, gagging, lacrimation and laryngospasm were lower as compared to the other two groups.
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J Anaesthesiol Clin Pharmacol · Jan 2011
Distance from Skin to Epidural Space: Correlation with Body Mass Index (BMI).
Epidural anaesthesia is being increasingly used to provide anaesthesia for surgery on the lower abdomen, perineum and lower extremities. However success of the epidural technique depends upon the correct identification of epidural space.2 We conducted a study to find the distance from skin to the epidural space and its correlation with body mass index, to improve the success rate. ⋯ WE FORMULATED PREDICTIVE EQUATION OF DEPTH OF EPIDURAL SPACE FROM SKIN IN RELATION TO BMI BASED ON LINEAR REGRESSION ANALYSIS AS: Depth (mm) = a + b (BMI). Where a = 17.7966 and b = 0.9777.
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J Anaesthesiol Clin Pharmacol · Jan 2011
Randomized double-blind comparison of ketamine-propofol and fentanyl-propofol for the insertion of laryngeal mask airway in children.
Till date, different combinations of adjuncts with induction agents have been tried for Laryngeal Mask Airway (LMA) insertion; yet, the ideal combination that provides the best insertion conditions with minimal side effects has not been identified, particularly in children. PATIENTS #ENTITYSTARTX00026; ⋯ The combination of fentanyl (2μg kg-1) and propofol (3.5mg kg-1) provides better conditions for LMA insertion in children than a combination of ketamine (0.5 mg kg-1) and propofol (3.5mg kg-1).
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J Anaesthesiol Clin Pharmacol · Jan 2011
Optimization of subarachanoid block by oral pregabalin for hysterectomy.
80% of patients undergoing surgical procedures experience postoperative pain1 and requires adequate pain relief. Nowadays drugs like COX2 inhibitors and calcium channel modulators (Pregabalin and Gabapentin) are been increasingly used for postoperative pain management effectively. We conducted this study to find whether preoperative pregabalin has any effect in postoperative analgesic requirement in patients undergoing hysterectomy under spinal anaesthesia. PATIENTS #ENTITYSTARTX00026; ⋯ Pregabalin being an oral drug which would be easy for the patients to take and also its prolongation of the neuraxial block helps in immediate postoperative analgesia and further reduction of other parentral analgesics. Pregabalin 150mg would be the optimal preemptive dose for hysterectomy under spinal anaesthesia.