Journal of anaesthesiology, clinical pharmacology
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J Anaesthesiol Clin Pharmacol · Jan 2011
Intrathecal sufentanil versus fentanyl for lower limb surgeries - a randomized controlled trial.
To compare the efficacy and safety of intrathecal sufentanil or fentanyl as adjuvants to hyperbaric bupivacaine in patients undergoing major orthopaedic lower limb surgeries in terms of onset and duration of sensory block, motor block and post-operative pain relief. PATIENTS #ENTITYSTARTX00026; ⋯ Intrathecal sufentanil (5 μg) and fentanyl (25 μg), as adjuvants lead to an earlier onset and prolonged duration of sensory block. The duration of effective analgesia with intrathecal sufentanil and fentanyl as adjuvants to hyperbaric bupivacaine is longer than that of bupivacaine alone.
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J Anaesthesiol Clin Pharmacol · Jan 2011
Evaluation of Intubating Conditions with Varying Doses of Propofol without Muscle Relaxants.
Since 1988 anaesthesiologist have proved that induction dose of propofol is sufficient to intubate patient without muscle relaxants. Propofol is unique in having property to suppress airway reflexes better than any other agent. Therefore study was undertaken to evaluate clinically acceptable intubating conditions with different doses of propofol without muscle relaxants. ⋯ Ideal intubating conditions without muscle relaxants can be achieved with propofol 3 mg kg(-1) with fentanyl 2 μg kg(-1) and lignocaine 1.5 mg kg(-1) without significant hemodynamic changes.
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J Anaesthesiol Clin Pharmacol · Jan 2011
Comparison of propofol based anaesthesia to conventional inhalational general anaesthesia for spine surgery.
Often conventional Inhalational agents are used for maintenance of anaesthesia in spine surgery. This study was undertaken to compare propofol with isoflurane anaesthesia with regard to haemodynamic stability, early emergence, postoperative nausea and vomiting (PONV) and early assessment of neurological functions. PATIENTS #ENTITYSTARTX00026; ⋯ Haemodynamic stability was comparable in both the groups. There was no significant difference in the recovery time between intravenous and inhalational group. Patients in propofol group were clear headed at awakening and were better oriented to place than inhalational group.
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J Anaesthesiol Clin Pharmacol · Oct 2010
A comparative study of two different doses of epidural neostigmine coadministered with lignocaine for post operative analgesia and sedation.
Adjuvants have been used to prolong analgesic effects of epidural local anaesthetics. We studied two different doses of neostigmine. PATIENTS #ENTITYSTARTX00026; ⋯ Co administration of epidural neostigmine and lignocaine appears to be a useful technique for postoperative analgesia as it increases the duration of analgesia and provides desirable sedation at the same time.