World journal of gastroenterology : WJG
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World J. Gastroenterol. · Jun 2010
Vitamin D receptor gene polymorphisms and hepatocellular carcinoma in alcoholic cirrhosis.
To assess the relationship between vitamin D receptor (VDR) gene polymorphisms and the presence of hepatocellular carcinoma (HCC). ⋯ VDR genetic polymorphisms are significantly associated with the occurrence of HCC in patients with liver cirrhosis. This relationship is more specific for patients with an alcoholic etiology.
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World J. Gastroenterol. · Jun 2010
Emodin enhances alveolar epithelial barrier function in rats with experimental acute pancreatitis.
To investigate the effect of emodin on expression of claudin-4, claudin-5 and occludin, as well as the alveolar epithelial barrier in rats with pancreatitis induced by sodium taurocholate. ⋯ Emodin attenuates pulmonary edema and inflammation, enhances alveolar epithelial barrier function, and promotes expression of claudin-4, claudin-5 and occludin in lung tissue samples from rats with acute pancreatitis.