World journal of gastroenterology : WJG
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To investigate the effectiveness of Clostridium novyi (C. novyi)-NT spores for the treatment of established subcutaneous pancreatic tumor in the syngeneic, immunocompetent Panc02/C57Bl/6 model. ⋯ The observed complete tumor regression is encouraging and shows that immunotherapy with C. novyi-NT is an interesting strategy for the treatment of pancreatic carcinomas of defined sizes.
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World J. Gastroenterol. · Jul 2010
Relationship between let-7a and gastric mucosa cancerization and its significance.
To investigate let-7a expression and analyze the correlation between let-7a and progression of gastric mucosa cancerization. ⋯ Gastric carcinoma has relatively lower expression of let-7a. Reduced let-7a may be a fundamental factor in the formation and lymph node metastasis of gastric carcinoma.
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World J. Gastroenterol. · Jul 2010
Controlled Clinical TrialSafety of same-day endoscopic ultrasound and endoscopic retrograde cholangiopancreatography under conscious sedation.
To assess the tolerability and safety of same-day tandem procedures, endoscopic ultrasound (EUS) followed by endoscopic retrograde cholangiopancreatography (ERCP) under conscious sedation. ⋯ Tandem EUS/ERCP procedure can be safely performed under conscious sedation with minimal adverse events. Combined procedures, however, are associated with higher dosages of sedatives, and slightly longer recovery time.
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World J. Gastroenterol. · Jul 2010
Randomized Controlled Trial Multicenter StudyCetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial.
To investigate efficacy and safety of cetuximab combined with two chemotherapy regimens in patients with unresectable metastatic colorectal cancer (mCRC). ⋯ This study confirms that combinations of cetuximab with FOLFOX6 or FOLFIRI are effective and significantly improve clinical outcome in KRAS wild-type compared with KRAS mutated mCRC.