World journal of gastroenterology : WJG
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World J. Gastroenterol. · May 2012
Clinical benefit of radiation therapy and metallic stenting for unresectable hilar cholangiocarcinoma.
To determine the efficacy of external beam radiotherapy (EBRT), with or without intraluminal brachytherapy (ILBT), in patients with non-resected locally advanced hilar cholangiocarcinoma. ⋯ Radiotherapy improved patient prognosis and the patency of uncovered metallic stents in patients with locally advanced hilar cholangiocarcinoma, but ILBT provided no additional benefits.
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World J. Gastroenterol. · May 2012
Randomized Controlled Trial Comparative StudyEndoclips vs large or small-volume epinephrine in peptic ulcer recurrent bleeding.
To compare the recurrent bleeding after endoscopic injection of different epinephrine volumes with hemoclips in patients with bleeding peptic ulcer. ⋯ Endoclip is superior to both small and large volume injection of epinephrine in the prevention of recurrent bleeding in patients with peptic ulcer.
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World J. Gastroenterol. · May 2012
CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer.
To investigate the relationship and molecular features of CD74/macrophage migration inhibitory factor (MIF)/Toll-like receptor 4 (TLR4) in gastric cancer. ⋯ Upregulation of MIF, CD74 and TLR4 are associated with increasing clinical stage and provide an opportunity as novel gastric cancer chemoprevention and/or treatment strategy.
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World J. Gastroenterol. · May 2012
Randomized Controlled Trial Multicenter StudyEfficacy and safety profile of LCR35 complete freeze-dried culture in irritable bowel syndrome: a randomized, double-blind study.
To assess the effects and safety of Lactobacillus casei rhamnosus LCR35 complete freeze-dried culture (LCR35) in patients suffering from irritable bowel syndrome (IBS). ⋯ This pilot study suggests that LCR35 could have some efficacy in IBS patients complaining of diarrhoea. These preliminary results need to be confirmed in larger studies.