World journal of gastroenterology : WJG
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World J. Gastroenterol. · Jun 2012
Review Meta AnalysisTwo-stage vs single-stage management for concomitant gallstones and common bile duct stones.
To evaluate the safety and effectiveness of two-stage vs single-stage management for concomitant gallstones and common bile duct stones. ⋯ Single-stage management is equivalent to two-stage management but requires fewer procedures. However, patient's condition, operator's expertise and local resources should be taken into account in making treatment decisions.
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World J. Gastroenterol. · Jun 2012
Randomized Controlled Trial Comparative StudyEffects of anesthetic methods on preserving anti-tumor T-helper polarization following hepatectomy.
To investigate the impact of different anesthetic techniques on T-helper (Th) cell subsets in hepatocellular carcinoma (HCC) patients undergoing hepatectomy. ⋯ G + E is superior to G in shifting the Th1/Th2 balance towards Th1, while decreasing Th17 and Treg, potentially benefiting HCC patients by promoting anti-tumor Th polarization.
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World J. Gastroenterol. · Jun 2012
Noninvasive assessment of hepatic fibrosis in Egyptian patients with chronic hepatitis C virus infection.
To evaluate the accuracy of specific biochemical markers for the assessment of hepatic fibrosis in patients with chronic hepatitis C virus (HCV) infection. ⋯ The use of AAR, APRI, API, GUCI and Pohl score measurements may decrease the need for liver biopsies in diagnosing cirrhosis, especially in Egypt, where resources are limited.
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World J. Gastroenterol. · Jun 2012
Multicenter Study Comparative StudyGlobulin-platelet model predicts minimal fibrosis and cirrhosis in chronic hepatitis B virus infected patients.
To establish a simple model consisting of the routine laboratory variables to predict both minimal fibrosis and cirrhosis in chronic hepatitis B virus (HBV)-infected patients. ⋯ By establishing a simple model using available laboratory variables, chronic HBV-infected patients with minimal fibrosis and cirrhosis can be diagnosed accurately, and the clinical application of this model may reduce the need for liver biopsy in HBV-infected patients.
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World J. Gastroenterol. · Jun 2012
Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis.
To investigate whether the patatin-like phospholipase domain containing-3 gene (PNPLA3) I148M polymorphism is associated with steatosis, fibrosis stage, and cirrhosis in hereditary hemochromatosis (HH). ⋯ The PNPLA3 I148M polymorphism may represent a permissive factor for fibrosis progression in patients with C282Y+/+ HH.