World journal of gastroenterology : WJG
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World J. Gastroenterol. · Nov 2016
Comparative StudyImpact of frailty on approach to colonic resection: Laparoscopy vs open surgery.
To understand the influence of frailty on postoperative outcomes for laparoscopic and open colectomy. ⋯ LC is associated with improved outcomes. Although the odds of mortality are higher in non-frail, there is a progressive increase in mortality with increasing frailty.
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World J. Gastroenterol. · Nov 2016
ReviewAcute kidney injury and post-reperfusion syndrome in liver transplantation.
In the past decades liver transplantation (LT) has become the treatment of choice for patients with end stage liver disease (ESLD). The chronic shortage of cadaveric organs for transplantation led to the utilization of a greater number of marginal donors such as older donors or donors after circulatory death (DCD). The improved survival of transplanted patients has increased the frequency of long-term complications, in particular chronic kidney disease (CKD). ⋯ Twenty-three studies were identified that specifically evaluated incidence, risk factors and outcome for patients developing PRS-induced AKI in liver transplantation. In order to identify intra-operative risk factors/mechanisms specifically involved in PRS-induced AKI, avoiding confounding factors, we have limited our study to "acute kidney injury AND DCD AND liver transplantation". Accordingly, three out of five studies were selected for our purpose.
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World J. Gastroenterol. · Nov 2016
Increased CD4+CD45RA-FoxP3low cells alter the balance between Treg and Th17 cells in colitis mice.
To investigate the role of regulatory T cell (Treg) subsets in the balance between Treg and T helper 17 (Th17) cells in various tissues from mice with dextran sulfate sodium-induced colitis. ⋯ Increased numbers of CD4+CD45RA-FoxP3low cells may cause an imbalance between Treg and Th17 cells that is mainly localized to the LPC rather than secondary lymphoid tissues.
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World J. Gastroenterol. · Nov 2016
Comparative StudyPresepsin teardown - pitfalls of biomarkers in the diagnosis and prognosis of bacterial infection in cirrhosis.
To evaluate the diagnostic and prognostic value of presepsin in cirrhosis-associated bacterial infections. ⋯ Presepsin is a valuable new biomarker for defining severe infections in cirrhosis, proving same efficacy as PCT. However, it is not a useful marker of short-term mortality.