World journal of gastroenterology : WJG
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World J. Gastroenterol. · Aug 2018
Review Comparative StudyCurrent guidelines for the management of non-alcoholic fatty liver disease: A systematic review with comparative analysis.
The current epidemic of non-alcoholic fatty liver disease (NAFLD) is reshaping the field of hepatology all around the world. The widespread diffusion of metabolic risk factors such as obesity, type2-diabetes mellitus, and dyslipidemia has led to a worldwide diffusion of NAFLD. In parallel to the increased availability of effective anti-viral agents, NAFLD is rapidly becoming the most common cause of chronic liver disease in Western Countries, and a similar trend is expected in Eastern Countries in the next years. ⋯ We distinguished guidelines from 5 different scientific societies whose reputation is worldwide recognised and who are representative of the clinical practice in different geographical regions. Differences were noted in: the definition of NAFLD, the opportunity of NAFLD screening in high-risk patients, the non-invasive test proposed for the diagnosis of NAFLD and the identification of NAFLD patients with advanced fibrosis, in the follow-up protocols and, finally, in the treatment strategy (especially in the proposed pharmacological management). These difference have been discussed in the light of the possible evolution of the scenario of NAFLD in the next years.
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World J. Gastroenterol. · Aug 2018
Observational StudyAltered oral microbiota in chronic hepatitis B patients with different tongue coatings.
To elucidate tongue coating microbiota and metabolic differences in chronic hepatitis B (CHB) patients with yellow or white tongue coatings. ⋯ This research illustrates specific clinical features and bacterial structures in CHB patients with different tongue coatings, which facilitates understanding of the traditional tongue diagnosis.
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World J. Gastroenterol. · Aug 2018
Herb-partitioned moxibustion alleviates colon injuries in ulcerative colitis rats.
To observe the effect of herb-partitioned moxibustion (HPM) on expression of colonic cytokines in ulcerative colitis (UC) rats. ⋯ HPM promotes the repair of colon injuries in UC rats, which is related to the regulation of several abnormally expressed cytokines.
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World J. Gastroenterol. · Aug 2018
Multicenter Study Observational StudyFatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients.