World journal of gastroenterology : WJG
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World J. Gastroenterol. · Aug 2018
Observational StudyAltered oral microbiota in chronic hepatitis B patients with different tongue coatings.
To elucidate tongue coating microbiota and metabolic differences in chronic hepatitis B (CHB) patients with yellow or white tongue coatings. ⋯ This research illustrates specific clinical features and bacterial structures in CHB patients with different tongue coatings, which facilitates understanding of the traditional tongue diagnosis.
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World J. Gastroenterol. · Aug 2018
Herb-partitioned moxibustion alleviates colon injuries in ulcerative colitis rats.
To observe the effect of herb-partitioned moxibustion (HPM) on expression of colonic cytokines in ulcerative colitis (UC) rats. ⋯ HPM promotes the repair of colon injuries in UC rats, which is related to the regulation of several abnormally expressed cytokines.
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World J. Gastroenterol. · Aug 2018
Multicenter Study Observational StudyFatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients.
To investigate if vitamin D deficiency is associated with fatigue in patients with inflammatory bowel disease (IBD). ⋯ In this study, no significant association between fatigue and vitamin D deficiency in IBD patients was revealed.
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World J. Gastroenterol. · Jul 2018
Systematic overview of hepatitis C infection in the Middle East and North Africa.
To assess the quality of and to critically synthesize the available data on hepatitis C infections in the Middle East and North Africa (MENA) region to map evidence gaps. ⋯ A substantial proportion of the reported outcomes may not help policymakers to develop micro-elimination strategies with precise HCV infection prevention and treatment programs in the region, as nowcasting HCV epidemiology using these data is potentially difficult. In addition to providing accurate information on HCV epidemiology, outcomes should also demonstrate practical and clinical significance and relevance. Based on the available data, most countries in the region have low to moderate anti-HCV prevalence. To achieve HCV elimination by 2030, up-to-date, good quality data on HCV epidemiology are required for the GP and key populations such as people who inject drugs and men who have sex with men.
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World J. Gastroenterol. · Jul 2018
Total polysaccharides of the Sijunzi decoction attenuate tumor necrosis factor-α-induced damage to the barrier function of a Caco-2 cell monolayer via the nuclear factor-κB-myosin light chain kinase-myosin light chain pathway.
To explore the protective effects and underlying mechanisms of total polysaccharides of the Sijunzi decoction (TPSJ) on the epithelial barriers in vitro. ⋯ Our results demonstrate that TPSJ alleviates the TNF-α-induced impairment of the intestinal epithelial cell barrier function by suppressing NF-κB p65-mediated phosphorylation of MLCK and MLC.