World journal of gastroenterology : WJG
-
World J. Gastroenterol. · Jan 2015
Morphologic factors of biliary trees are associated with gallstone-related biliary events.
To determine the risk factors for gallstone-related biliary events. ⋯ These findings will help guide the treatment of patients with asymptomatic gallstones. Clinicians should closely monitor patients with asymptomatic gallstones who exhibit these characteristics.
-
World J. Gastroenterol. · Jan 2015
Observational StudyFatty acid changes help to better understand regression of nonalcoholic fatty liver disease.
To investigate whether liver steatosis reduction due to a six-month dietary intervention results in significant changes in the concentrations of fatty acids. ⋯ Liver steatosis reduction is associated with changes in fatty acid profiles, and these changes may reflect an alteration in fatty acid synthesis and metabolism. These findings may help better understand regression of nonalcoholic fatty liver disease.
-
World J. Gastroenterol. · Jan 2015
Altered vasoactive intestinal peptides expression in irritable bowel syndrome patients and rats with trinitrobenzene sulfonic acid-induced colitis.
To investigate the vasoactive intestinal peptides (VIP) expression in irritable bowel syndrome (IBS) and trinitrobenzene sulfonic acid (TNBS) induced colitis. ⋯ Alterations in VIP expression may play a role in IBS. Therefore, a better understanding of the physiology of VIP could lead to new therapeutics.
-
World J. Gastroenterol. · Jan 2015
Enterocyte dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin expression in inflammatory bowel disease.
To investigate dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) expression in intestinal epithelial cells (IECs) in inflammatory bowel disease (IBD). ⋯ IECs regulate tissue-associated immune compartments under the control of DC-SIGN in IBD.
-
World J. Gastroenterol. · Dec 2014
2,4,6-trinitrobenzene sulfonic acid-induced chronic colitis with fibrosis and modulation of TGF-β1 signaling.
To investigate whether targeting proteasome might reverse intestinal fibrosis in rats. ⋯ Rats with TNBS-induced chronic colitis exhibited colon fibrosis associated with higher TGF-β signaling. Proteasome inhibition by bortezomib had no effect on fibrosis in our experimental conditions.