Postgraduate medicine
-
Postgraduate medicine · Mar 2021
Sex-specific cardiac and vascular responses to hypertension in Chinese populations without overt cardiovascular diseases.
The aim of current study was to evaluate sex-specific cardiac and vascular responses to hypertension in Chinese populations without overt cardiovascular disease. ⋯ In conclusion, the current study indicates cardiac and vascular responses to hypertension are greater in women than in men, manifesting as an increased estimated LV filling pressure and arterial elastance in women.
-
Postgraduate medicine · Mar 2021
Case ReportsAcute fluconazole toxıcıty: a case presentıng wıth protean manıfestatıons ıncludıng systemıc and neurologıc symptoms.
Neurologic adverse effects of triazole antifungal compounds used for the treatment of systemic and deep mycoses are relatively rare. The most common presentation is the involvement of peripheral nervous system, usually presenting with subjective symptoms such as paresthesia, dysesthesia, or numbness. Among these compounds, fluconazole has relatively more frequent neurological adverse reactions. ⋯ This unusual combination of these rare adverse reactions of fluconazole may be explained by activation of an immune mechanism triggered by the drugs and genetic factors, or some other unknown individual factors. This case is reported due to the presence of rare systemic and neurologic adverse events of fluconazole, leading to this unusual clinical picture. We would like to emphasize fluconazole-related systemic and neurologic adverse reactions with life-threatening potential should be kept in mind.
-
Postgraduate medicine · Mar 2021
Trends and outcomes of venous thromboembolism in adult hospitalizations with acute myeloid leukemia: analysis of nationwide inpatient sample from 2010 to 2014.
Background: Venous thromboembolism (VTE) occurs frequently in acute myeloid leukemia (AML) patients. There are no population-based studies from the United States (U. S.) analyzing this association. ⋯ S. After adjusting for confounders, increasing age, Black race, and lack of insurance were found to have higher risk of in-hospital mortality in the AML-VTE cohort. The odds of in-hospital mortality in AML hospitalizations with VTE are not higher than those without VTE.
-
Postgraduate medicine · Mar 2021
ReviewHeart failure with preserved ejection fraction: Disease burden for patients, caregivers, and the healthcare system.
Heart failure with preserved ejection fraction (HFpEF) will soon become the most prevalent form of HF because of an aging population and an accompanying increase in the number of risk factors for this disease. The high frequency of comorbidities typical of this population contributes to an increased risk for hospitalization and death. ⋯ Financial burden is associated with HFpEF, stemming from hospitalization and long-term care costs, as well as absenteeism from work in the case of caregivers. Early identification of patients at risk and aggressive management are key to preventing this disease and its progression.