Postgraduate medicine
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Postgraduate medicine · Nov 2022
ReviewStepwise approach to continuous glucose monitoring interpretation for internists and family physicians.
Continuous glucose monitoring (CGM) use has expanded rapidly in recent years among people with both type 1 and type 2 diabetes. In concert with the globally increasing prevalence of type 2 diabetes, the majority of whom receive diabetes care from internists or family physicians rather than specialists, it is becoming increasingly incumbent upon physicians within internal medicine and family practice to interpret and utilize CGM data in real-world clinical practice. ⋯ Given the limited amount of time available to internists and family physicians to address multiple complex topics in a typical office visit, a pragmatic, simple, and systematic approach to CGM interpretation is crucial. This article aims to provide internists and family physicians with a simplified and systematic approach to CGM interpretation that can be easily and efficiently implemented in a brief office visit.
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Postgraduate medicine · Nov 2022
ReviewCeliac disease and idiopathic pulmonary hemosiderosis: a literature review of the Lane-Hamilton syndrome.
Lane-Hamilton syndrome (LHS) presents a medical emergency, with 14% mortality due to Idiopathic Pulmonary Hemosiderosis (IPH) in acute phase. Despite the clinical severity of this entity, there has been no published review in the international literature, resulting in lack of awareness and delayed diagnosis. A rigorous search of international databases yielded a total of 80 LHS cases from January 1971 to August 2020. ⋯ Three cases with severe respiratory failure or hemodynamic instability were intubated and a further three succumbed. A thorough understanding of LHS may reveal further diagnostic indexes and a consensus on therapy guidelines. Screening for CD is essential in all IPH cases for timely recognition and favorable outcome.
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Postgraduate medicine · Nov 2022
ReviewRole of RAGE and its ligand HMGB1 in the development of COPD.
Smoking is a well-established risk factor for chronic obstructive pulmonary disease (COPD). Chronic lung inflammation continues even after smoking cessation and leads to COPD progression. ⋯ Moreover, RAGE is involved in the physiological response to cigarette smoke exposure. Since innate and acquired immunity plays an essential role in the development of chronic inflammation and emphysema in COPD, here we summarized the roles of RAGE and its ligand HMGB1 in COPD immunity.
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Postgraduate medicine · Nov 2022
Machine learning model for predicting 1-year and 3-year all-cause mortality in ischemic heart failure patients.
Machine learning (ML) model has not been developed specifically for ischemic heart failure (HF) patients. Whether the performance of ML model is better than the MAGGIC risk score and NT-proBNP is unknown. The current study was to apply ML algorithm to build risk model for predicting 1-year and 3-year all-cause mortality in ischemic HF patient and to compare the performance of ML model with the MAGGIC risk score and NT-proBNP. ⋯ ML models predicted prognosis in ischemic HF with good discrimination and well calibration. These models may be used by clinicians as a decision-making tool to estimate the prognosis of ischemic HF patients.
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Postgraduate medicine · Nov 2022
Review Meta AnalysisPostoperative complications, length of stay, and mortality following colectomies in rural hospitals: a systematic review and meta-analysis.
Studies regarding patients who have underwent colectomy reported contradictory post-surgical complications based on their living areas. Due to the conflicting data surrounding whether rural or urban hospitals have lower postoperative complication rates, we have performed a systematic review and meta-analysis with the aim of understanding and assessing the evidence that has already been found. ⋯ Rural hospitals overall have equivalent postoperative complication rates to urban hospitals and can provide sufficient postoperative patient care.