Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakológiai Egyesület lapja = official journal of the Hungarian Association of Psychopharmacology
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Neuropsychopharmacol Hung · Dec 2010
Review[Trazodone--its multifunctional mechanism of action and clinical use].
Trazodone is an antidepressant of the serotonin (5-HT2) antagonist and reuptake inhibitor class, and has been considered to act as a multifunctional drug. It is generally approved for the treatment of major depression, its efficacy is well-documented in elderly patients, and it has been widely used for replacement of benzodiazepines or benzodiazepine-type sleeping drugs due to its anxiolytic efficacy and sleep normalizing effect in depression. ⋯ It is weight neutral and does not decrease sexual function. The introduction of trazodone to the Hungarian market may decrease the widespread use of benzodiazepines in antidepressive treatment.
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Neuropsychopharmacol Hung · Dec 2010
Barriers to antiviral treatment in hepatitis C infected intravenous drug users.
Nowadays intravenous drug use is the main source of hepatitis C transmission, but only a small proportion of those who acquired infection via intravenous drug use receive antiviral treatment. ⋯ The low proportion of patients entering antiviral treatment calls the attention to further improving the pretreatment management of this patient population. Special attention should be paid to the maintenance of abstinence.