Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Dec 2014
[Analysis on risk factors of endotracheal cuff under inflation in mechanically ventilated patients].
To investigate the prevalent condition of endotracheal cuff pressure and risk factors for under inflation. ⋯ Abnormal endotracheal cuff pressure is common in critically ill patients with intratracheal intubation. Duration of intubation is associated with under inflation of the cuff, and it calls for strengthening monitoring and management.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Dec 2014
[Effect of airway humidification on lung injury induced by mechanical ventilation].
To explore the effect of airway humidification on lung injury as a result of mechanical ventilation with different tidal volume (VT). ⋯ Airway humidification can alleviate pathological lung injury, damage of cilia and cellular structure in trachea caused by mechanical ventilation with low and high V(T). High V(T) with humidification can result in serious pulmonary edema.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Dec 2014
[The impacts of regulating Toll-like receptor 2/nuclear factor-ΚB signal pathway on rats with ventilator-induced lung injury].
To evaluate the role of Toll-like receptor 2/nuclear factor-ΚB (TLR2/NF-ΚB) signaling pathway pretreatment in ventilator-induced lung injury (VILI). ⋯ To some extent, pre-intervention with TLR2mAb to block the TLR2/NF-ΚB signal pathway can inhibit the release of pro-inflammatory factors, and regulate the VILI.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Dec 2014
[Role of Foxp3/Treg and RORγt/Th17 cell imbalance in rat model of chronic obstructive pulmonary disease].
To observe the changes in forkhead/winged helix transcription factor p3(Foxp3), regulatory T cells (Treg), retinoid-related orphan receptor gamma (RORγt) in rat model of chronic obstructive pulmonary disease (COPD). ⋯ There is a relationship among decreased pulmonary function, inflammation and imbalance of Foxp3/Treg and RORγt/Th17 in COPD.