Zhonghua wei zhong bing ji jiu yi xue
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2019
[Prediction value of plasma histone in prognosis of sepsis patients].
To explore the value of plasma histones in predicting the prognosis of sepsis patients. ⋯ The independent risk factors for ICU mortality of sepsis patients were high histone level and the use of vasopressor. Plasma histone can be regarded as an indicator in predicting the prognosis of patients with sepsis.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2019
[Characteristics and failure risk factors of sequential high-flow nasal cannula oxygen therapy after weaning from invasive ventilation in patients of surgical intensive care unit].
To investigate the characteristics and failure risk factors of sequential high-flow nasal cannula oxygen therapy (HFNC) after weaning from invasive ventilation. ⋯ HFNC is one of the commonly used oxygen therapy methods in the ICU, but not all patients who are treated as a sequential therapy after invasive mechanical ventilation weaning can benefit from it. SOFA score, BNP before HFNC treatment and HR after 30 minutes HFNC treatment were independent risk factors of HFNC failure. Each independent risk factor and regression model can predict the success of HFNC treatment.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2019
[Study on the levels of main inflammatory factors in septic shock and their clinical significance].
To explore the correlation between major inflammatory factors and septic shock in intensive care unit (ICU) patients, and to provide a basis for the diagnosis and treatment of septic shock. ⋯ The levels of inflammatory factors CRP, NT-proBNP, TNF-α, PCT and IL-6 were significantly increased, which were important factors for early diagnosis of septic shock.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2019
[Experimental study on the mechanism of glycogen synthase kinase-3β inhibitor on acute kidney injury of acute necrotizing pancreatitis in rats].
To explore the protective mechanism of glycogen synthase kinase-3β (GSK-3β) inhibitor TDZD-8 on acute necrotizing pancreatitis (ANP) associated kidney injury in rats. ⋯ Blockade of GSK-3β activity by TDZD-8 exerts the protective effect against kidney injury by inhibiting the inflammation signaling pathway in ANP. It can alleviate histopathological and ultrastructural changes in kidney injury, which protection mechanism is mediated by NF-ΚB and its related inflammatory mediators.