Zhonghua wei zhong bing ji jiu yi xue
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jul 2018
Observational Study[Clinical study of vancomycin for appropriate dosing in severe infective patients with augmented renal clearance].
To explore the impact of augmented renal clearance (ARC) on vancomycin pharmacokinetic target attainment in severe infective patients, and to analyze the initial dose of vancomycin based on the measured 12-hour urinary creatinine clearance (12 h-CLCR). ⋯ Patients with ARC have low concentrations of vancomycin and often fail to achieve therapeutic target. The initial dose of vancomycin can be selected according to 12 h-CLCR, the higher the 12 h-CLCR, the more the dosage of vancomycin is. When 12 h-CLCR is greater than or equal to 69.83 mL×min-1×1.73 m-2, the dosage of vancomycin should be higher than the conventional dosage.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jul 2018
[Value of Hepcidin as a diagnostic biomarker of sepsis in critically ill adults].
To investigate the diagnostic value of Hepcidin as a sepsis biomarker in critically ill adults. ⋯ China Clinical Trial Registration Center, ChiCTR-DDD-16008522.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jul 2018
[Ultrasonic monitoring of carotid blood flow in interposed abdominal pulling-pressing cardiopulmonary resuscitation].
To explore the difference in ultrasonic monitoring in carotid blood flow, resuscitation effects and prognosis between interposed abdominal pulling-pressing cardiopulmonary resuscitation (IAPP-CPR) and standard cardiopulmonary resuscitation (STD-CPR). ⋯ IAPP-CPR was superior to traditional STD-CPR in improving arterial blood flow and resuscitation effect, but no superiority was found in ROSC rate and survival rate, which may be relate to the small number of patients that included in this study. More clinic trials are needed.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jul 2018
[Dose and timing of normal saline resuscitation on endothelial glycocalyx in early septic shock].
To observe the effect of different doses and timing of normal saline (NS) resuscitation combined with norepinephrine (NE) on endothelial glycocalyx in rabbits with early septic shock. ⋯ The dose and timing of resuscitation with NS in septic shock can affect pulmonary vascular endothelial glycocalyx function. The timely resuscitation with 30 mL NS in combination with NE plays a protective effect on endothelial cell and glycocalyx. However, NS resuscitation which was not timely or excessive infusion can make the glycocalyx degradation more obvious, resulting in increased endothelial permeability, microcirculation damaged, thus aggravate lung injury.
-
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Jun 2018
[Effect of early rehabilitation physiotherapy on muscle quality and function in critically ill patients].
To investigate the effect of early rehabilitation physiotherapy on muscle quality and function in critical patients. ⋯ Early rehabilitation physiotherapy can improve the muscle quality and function in critical patients, and decrease the length of ICU stay.