Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Dec 2015
[Effects of mitochondrial division inhibitor on neurological function and neuronal apoptosis in rats after cardiopulmonary resuscitation].
To investigate the effects of mitochondrial division inhibitor 1 (mdivi-1) in rats after cardiopulmonary resuscitation (CPR) and its mechanism. ⋯ By inhibiting mitochondrial Cyt-C apoptotic pathway to reduce neuronal apoptosis in rats after CA-CPR, mdivi-1 can improve brain function after CPR.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Nov 2015
[Improvement effect of early goal-directed therapy on the prognosis in patients with septic shock].
To evaluate the effect of the early goal-directed therapy (EGDT) on mortality in patients with septic shock, and to analyze the risk factors of mortality. ⋯ Mortality was as high as 68.96% during 10 years when the period before the use of 2004 SSC, and the mortality rate was lowered to 34.21% during 10 years during which the early fluid resuscitation treatment was based on EGDT. Aging and failure of more than 2 organs were independent risk factors for mortality in patients with septic shock. Compared with reaching the standard of EGDT within 24 hours, reaching the standard of EGDT within 6 hours can rapidly reverse hypoxic-ischemic tissue, thereby improving the prognosis of the patient with lowering of mortality rate.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Nov 2015
[Effect of esmolol on fluid responsiveness and hemodynamic parameters in patients with septic shock].
To study the effects of esmolol on fluid responsiveness and hemodynamic parameters in patients with septic shock. ⋯ Heart rate control with esmolol infusion may reduce fluid responsiveness, cardiac function, heart rate and cardiac output without adverse effect on systemic perfusion in septic shock patients.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Nov 2015
[A new score system for prediction of death in patients with severe trauma: the value of death warning score].
To discuss a best predictive score index in predicting death in patients with severe trauma, death warning score, and to provide a simple score for clinical use. ⋯ Age ≥ 65 years, APACHE II score ≥ 21, GCS < 6, severe sepsis or septic shock were the risk factors of death in patients with severe trauma, and they can be considered as warning score of death in patients with severe trauma. With the score mortality can be better predicted than any other kind of score for patients with severe trauma.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Nov 2015
[Analysis of risk factor of hyperlactacidemia after gastrointestinal surgery: a clinical data analysis of 216 patients].
To investigate the risk factors that cause arterial blood lactate (Lac) elevation in patients after gastrointestinal operation. ⋯ The surgical site showed an influence on the occurrence of hyperlactacidemia in patients after gastrointestinal operation, and the lowest occurrence rate was found in the colonic operation. In patients suffering from gastrointestinal operation, antibiotics should be routinely used to improve MAP. Excessive preoperative and intraoperative fluid infusion cannot reduce the occurrence of hyperlactacidemia.