Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Oct 2015
[Role and mechanism of the NOD-like receptor 3 inflammasome in ventilator-induced lung injury in rats].
To investigate the role and its mechanism of the NOD-like receptor 3 (NLRP3) inflammasome in alveolar macrophages in ventilator-induced lung injury (VILI) in rats. ⋯ NLRP3 inflammasome in alveolar macrophages may be involved in the mechanism of occurrence of VILI.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2015
Meta Analysis[Effect of timing of initiation of renal replacement therapy on prognosis in septic patients with acute kidney injury: a Meta analysis].
To systemically review the effects of timing of initiation of renal replacement therapy (RRT) on prognosis in septic patients with acute kidney injury (AKI). ⋯ Early RRT could reduce the 28-day mortality in patients with septic AKI compared with late RRT, but it did not lower the total mortality.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2015
Meta Analysis[Accuracy of procalcitonin for diagnosis of sepsis in adults: a Meta-analysis].
To assess the clinical value of procalcitonin (PCT ) in the diagnosis of sepsis in adults. ⋯ Our results indicate a moderate degree of value of PCT for diagnosis of sepsis in adult patients. The diagnostic accuracy in medical patients is higher than that in surgical patients. PCT is a good auxiliary biomarker for diagnosis of sepsis.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2015
Randomized Controlled Trial[Esmolol improves clinical outcome and tissue oxygen metabolism in patients with septic shock through controlling heart rate].
To investigate whether esmolol could improve clinical outcome and tissue oxygen metabolism by controlling heart rate (HR) in patients with septic shock. ⋯ The results demonstrate that HR controlled by a titrated esmolol infusion given to septic shock patients was associated with an improvement in tissue metabolism, reduction in the length of ICU stay and lowering of 28-day mortality.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2015
Meta Analysis[Effect of early goal-directed therapy on mortality in patients with severe sepsis or septic shock: a Meta analysis].
To investigate whether early goal-directed therapy (EGDT) could improve the mortality rate in patients with severe sepsis or septic shock. ⋯ EGDT was associated with significant improvement in short-term mortality but not with long-term mortality in patients with severe sepsis or septic shock. Grade C was recommended by our study.