Acta neurochirurgica. Supplement
-
Acta Neurochir. Suppl. · Jan 2011
Anatomic study in cadaver of the motor branch of the musculocutaneous nerve.
This study of 80 cadavers demonstrates that the anatomic position of the motor branch of the musculocutaneous nerve with respect to that of the sensitive branch of the same nerve is lateral in more than 88% of cases in humans.The distance from plexus to the separation into the motor and sensitive fascicles was 8-9 cm long.Given the lateral position of the motor component of the musculocutaneous nerve, the nerves that are going to be used to neurotize this area can be directed so as to increase the efficacy of the results for the flexor function of the arm. ⋯ If the nerves that are to be used for neurotization of the musculacutaneous nerve are directly taken to the lateral fascicle of that nerve, which is generally the motor component, the treatment should be effective and should avoid the loss of motor axons resulting from anastomosing to the sensitive fascicle.
-
Acta Neurochir. Suppl. · Jan 2011
Clinical requirements and possible applications of robot assisted endoscopy in skull base and sinus surgery.
Functional Endoscopic Surgery of Paranasal sinuses (FESS) and Skull Base surgery is one of the most frequent surgeries performed at the ENT department of the Bonn University, Germany. Beside of surgical Navigation Robotic is one of the upcoming fields of Computer assisted Surgery developments. This work presents novel research and concepts for Robot Assisted Endoscopic Sinus Surgery (RASS) of the Paranasal sinuses and the anterior Skull Base containing the analysis of surgical workflows, the segmentation and modelling of the Paranasal sinuses and the anterior Skull Base and the development of the robotic path planning. An interdisciplinary group of software engineers and surgeons in Braunschweig and Bonn, Germany are approximate to solutions by a clinical and technical research program financed through the DFG (Deutsche Forschungsgemeinschaft, German research Community).
-
Acta Neurochir. Suppl. · Jan 2011
Mechanism of action of oxygen ozone therapy in the treatment of disc herniation and low back pain.
In the low back syndrome the pain has a multifactorial origin and ozone can surprisingly display a number of beneficial effects ranging from the inhibition of inflammation, correction of ischemia and venous stasis, and finally inducing a reflex therapy effect by stimulating anti-nociceptor analgesic mechanisms. The intradiscal and intramuscular injection of oxygen-ozone is a successful approach comparable to other minimally invasive procedures, but the elucidation of the mechanisms of action remains elusive. This communication shortly reports the mechanisms of action of oxygen ozone therapy at the level of intervertebral disc and paravertebral muscles.
-
Acta Neurochir. Suppl. · Jan 2011
Matrix metalloproteinase 9 inhibition reduces early brain injury in cortex after subarachnoid hemorrhage.
This study investigated the role of matrix metalloproteinase-9 (MMP-9) in early brain injury (EBI) after subarachnoid hemorrhage (SAH). Sprague-Dawley male rats (n=30) between 250 and 300 g were used. SAH was produced by injecting autologous arterial blood into the prechiasmatic cistern. ⋯ Laminin, the substrate of MMP-9, was decreased at 24h after SAH, and SB-3CT prevented laminin degradation. The number of TUNEL-positive neurons in cerebral cortex was increased after SAH and decreased by SB-3CT (P<0.01). MMP-9 may be involved in EBI after SAH and inhibition of MMP-9 may reduce EBI in cerebral cortex.
-
Acta Neurochir. Suppl. · Jan 2011
Deferoxamine reduces early brain injury following subarachnoid hemorrhage.
The effect of subarachnoid hemoglobin on neuroglial cells contributing to early brain injury is unclear. Several intracerebral hemorrhage studies indicated that pathological iron deposition in the brain contributes to secondary brain injury. Therefore, the purpose of this study was to investigate the relationship between iron and neuroglial cell changes following SAH, and examine the effect of deferoxamine (DFX). ⋯ DFX treatment reduced brain non-heme iron concentration, ferritin expression and neuronal cell death at day 3 (P < 0.01) following SAH. These results suggest that excessive hemoglobin and iron overload play an important role in early brain injury following SAH. Acute treatment with DFX significantly ameliorates neuronal cell death and may be a potential therapeutic agent for SAH.