Acta neurochirurgica. Supplement
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Acta Neurochir. Suppl. · Jan 2011
Clinical study of changes of cerebral microcirculation in cerebral vasospasm after SAH.
Aim to investigate the changes of cerebral microcirculation after subarachnoid hemorrhage (SAH) and its association with cerebral vasospasm (CVS) after SAH. CTP was performed in 85 patients with SAH and 35 controls. Cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) were recorded for final analysis. ⋯ In 46 CVS patients, sCVS group presented significantly lower CBF and more prolonged MTT than asCVS patients (P<0.05). Seven cases with MTT between 6.31 and 12.72 s showed delayed ischemic neurological deficit (DIND), two of whom had hemiplegia, and one died. Our findings suggest that CTP examination contributes to uncover the changes of cerebral microcirculation after SAH, and the changes of cerebral microcirculation are associated with CVS post SAH.
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Acta Neurochir. Suppl. · Jan 2011
Electrocardiographic abnormalities in patients with intracerebral hemorrhage.
Stroke is frequently followed by electrocardiographic changes. Although electrocardiographic abnormalities are well known in ischemic stroke and subarachnoid hemorrhage, these changes have only rarely been investigated systematically in patients with intracerebral hemorrhage. The purpose of this study is to investigate the prevalence and characterization of ECG abnormalities in a consecutive series of ICH patients who had no history of heart disease. ⋯ Electrocardiographic abnormalities frequently occur after intracerebral hemorrhage, and these changes were not related to the level of the cerebral lesion, but were related to the location of the cerebral lesion and the outcome.
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Acta Neurochir. Suppl. · Jan 2011
Analysis on death-associated factors of patients with subarachnoid hemorrhage during hospitalization.
The prognosis of patients with high-clinical-score subarachnoid hemorrhage remains poor, with early high mortality rate. Therefore, to predict the early outcome of patients after subarachnoid hemorrhage, several clinical factors were hypothesized to be related to death during hospitalization. ⋯ Increased white blood cell count may indicate poor outcomes for patients during hospitalization, even early death.
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Studies have shown that weekend admissions are associated with outcomes of patients with different diseases. Our aim is to evaluate the weekend effects in patients with intracerebral hemorrhage (ICH) in our hospital. A retrospective analysis of patients with ICH was performed. ⋯ Weekend admission was not a statistically significant predictive factor for in-hospital mortality (P=0.315) and functional outcomes (P=0.128) in patients with ICH. However, a significant correlation was found between the ICH score and the mortality (OR=6.819, 95%CI: 4.323-10.757; P=0.009). Our results suggest that compared with weekday admission, weekend admission is not significantly associated with increased short-term mortality and poorer functional outcome among patients hospitalized with ICH.
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Acta Neurochir. Suppl. · Jan 2011
Clinical requirements and possible applications of robot assisted endoscopy in skull base and sinus surgery.
Functional Endoscopic Surgery of Paranasal sinuses (FESS) and Skull Base surgery is one of the most frequent surgeries performed at the ENT department of the Bonn University, Germany. Beside of surgical Navigation Robotic is one of the upcoming fields of Computer assisted Surgery developments. This work presents novel research and concepts for Robot Assisted Endoscopic Sinus Surgery (RASS) of the Paranasal sinuses and the anterior Skull Base containing the analysis of surgical workflows, the segmentation and modelling of the Paranasal sinuses and the anterior Skull Base and the development of the robotic path planning. An interdisciplinary group of software engineers and surgeons in Braunschweig and Bonn, Germany are approximate to solutions by a clinical and technical research program financed through the DFG (Deutsche Forschungsgemeinschaft, German research Community).