The Journal of burn care & rehabilitation
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J Burn Care Rehabil · Jul 1999
Randomized Controlled Trial Clinical TrialThe search for cost-effective prevention of postoperative nausea and vomiting in the child undergoing reconstructive burn surgery: ondansetron versus dimenhydrinate.
Postoperative nausea and vomiting (PONV) is a common and unpleasant problem for children with burns who are undergoing reconstructive burn surgery. Ondansetron and dimenhydrinate have been found to be effective for the prevention of PONV in other patient populations, but they have not been directly compared in the pediatric population. A prospective, randomized, double-blind, placebo-controlled comparison of ondansetron and dimenhydrinate was performed. ⋯ The differences between ondansetron and dimenhydrinate were not significant. The average cost to our pharmacy for the prescribed dose of ondansetron was $19.34; the cost for dimenhydrinate was $0.90. In this patient population, dimenhydrinate was as effective as ondansetron for the prevention of PONV and postoperative vomiting, and it was much less expensive.
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J Burn Care Rehabil · Jul 1999
Randomized Controlled Trial Comparative Study Clinical TrialSafety and efficacy of TransCyte for the treatment of partial-thickness burns.
Standard treatment for extensive partial-thickness burns in the United States and in much of the world involves the application of topical antimicrobial agents and repetitive wound débridements and dressing changes. We evaluated a new biologic wound covering, TransCyte (Advanced Tissue Sciences, La Jolla, Calif, formerly marketed as Dermagraft-Transitional Covering), for the treatment of partial-thickness burns. This material is composed of human newborn fibroblasts which are then cultured on the nylon mesh of Biobrane (Dow B. ⋯ There were no infections in the 32 wound sites treated with TransCyte. In the first study group, late wound evaluations (3, 6, and 12 months postburn) were performed with use of the Vancouver Scar Scale. The results indicated that wound sites treated with TransCyte healed with less hypertrophic scarring than sites treated with silver sulfadiazine (P < .001 at 3 and 6 months, P = .006 at 12 months).
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J Burn Care Rehabil · Jul 1999
Personality traits and psychosocial adjustment of patients with burns.
Existing literature demonstrates a relationship between selected personality traits and coping, a relationship explored here in a sample of 61 male Israeli patients with burns. Successful coping was assessed by the 5-item Satisfaction With Life Scale and 2 single-item measures of adjustment to the specific injury. ⋯ The importance of a patient's ability to elicit social support as a means of coping was also considered. Psychologic intervention is suggested as a consequence of the results obtained.