Laryngologie, Rhinologie, Otologie
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Laryngol Rhinol Otol (Stuttg) · Oct 1986
Biography Historical Article[Was Beethoven's deafness caused by Paget's disease? Report of findings and study of skull fragments of Ludwig van Beethoven].
Paget's disease of bone (osteitis deformans) has been repeatedly named as a possible cause for Ludwig van Beethoven's deafness. In 1985 a descendent of Franz Romeo Seligmann (a Viennese medical historian who in 1863 had studied Beethoven's mortal remains on the occasion of their relocation) presented to us three bone fragments allegedly from Beethoven's cranium. ⋯ They did not show signs of Paget's disease of bone. It must therefore be concluded that Beethoven's deafness was not caused by Paget's osteitis deformans.
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Laryngol Rhinol Otol (Stuttg) · Oct 1986
[Edema prevention with aprotinin in elective interventions in the area of the jaw and face (preliminary results)].
The effect of aprotinin on oedema prevention and pain following different maxillo-facial surgical interventions has been recorded in an open, non-comparative pilot study with 87 patients. After high dosage application of the proteinase inhibitor aprotinin only few cases exhibited a fully developed oedema and tension pain in the postoperative period. Postoperative wound-healing appeared also remarkably convenient. Incidence and severity of the postoperative swelling were altogether distinctly reduced in comparison to what would have been expected as the usual postoperative clinical condition of such patients.