Läkartidningen
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Biography Historical Article
[Four surgeons introduced ether inhalation in Sweden. Then the anesthesiology was put to sleep for 100 years].
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Review Historical Article
[Oligodendrocytes have a key role in the development of CNS function and in myelin related diseases].
Oligodendrocytes provide CNS axons with myelin sheaths through processes of various lengths. The lipid-rich myelin insulates axons electrically, which increases conduction velocity. ⋯ A number of genetically manipulated animal models have provided insights regarding myelination and the function of myelin components. Current research on myelin related diseases, i.e. multiple sclerosis, focus on novel strategies for remyelination through transplantation of myelinating cells or stimulation of endogenous oligodendrocytes.