Läkartidningen
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Biography Historical Article
["Doctor Gas" served his country for good and bad].
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A 19-year old female was admitted with intractable nausea, vomiting and intermittent abdominal pain. The medical history of the patient contained nine previous, similar admissions and extensive investigations within several medical specialties at several hospitals in the vicinity of Copenhagen, as well as abroad during the patient's holidays. All of the investigations were without findings that could explain the recurring condition. ⋯ She received parenteral rehydration and counseling regarding cannabis cessation. Two months after discharge the patient was no longer using cannabis and was symptom-free. This case report intends to raise clinicians' awareness of CHS in Sweden, a country where 55 000 of the inhabitants aged 16 years and older report having used cannabis during the past 30 day period.
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The inner side of the endothelium is covered by a thin layer of glycosylated proteins called the glycocalyx, which binds plasma to its surface up to a total thickness of 1-3 µm. The glycocalyx governs the endothelial permeability for macromolecules and has a key role in the regulation of microvascular perfusion. ⋯ The glycocalyx is involved in the initiation of the inflammatory response and is easily broken down (shedded) in response to sepsis, trauma, surgery, and cardiovascular disease. A shedded glycocalyx layer seems to impair the prognosis of heart failure and kidney disease. Its role as a mediator of cardiovascular complications to chronic disease is currently an important research topic.