Nihon rinsho. Japanese journal of clinical medicine
-
Depression is the most common complication in perinatal period, affecting approximately 10% of women. Studies were also examined for data related to the predictors/risk factors, effects on the fetus and newborn, and treatment of depression during these periods. Psychopharmacological treatment in pregnant or breastfeeding women with depression will result primarily from a careful evaluation of their psychopathological condition. ⋯ Prevention and psychological intervention is also useful for detecting mother with postnatal depression, using the EPDS. Controlled psychological trials for postnatal depression have shown the benefit of involving health professionals. Multidisciplinary specialist teams in mother and baby units have been an important role in perinatal psychiatric care.
-
We described clinically features of inherited prion disease (GSS, familial CJD and FFI). In addition, we found new useful findings of GSS patients for early diagnosis. Generally, clinicians believe that the main features of GSS (P102L) are cerebellar symptoms and dementia; however, our patients showed other features. ⋯ Dementia was not a main symptom during the early stage. The key features for the early diagnosis of GSS102 are truncal ataxia, dysesthesia and hyporeflexia of the lower legs, and mild dysarthria. Normal cerebellar MRI and abnormal cerebral SPECT findings should be useful for early diagnosis of GSS (P102L).