Acta anaesthesiologica Scandinavica. Supplementum
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Acta Anaesthesiol Scand Suppl · Jan 1975
Comparative Study Clinical Trial Controlled Clinical TrialA double-blind comparison of single doses of etidocaine 1 % and bupivacaine 0.5 % during continuous lumbar epidural block in obstetrics.
A double-blind investigation of some of the effects of etidocaine 1 % and bupivacaine 0.5 % was undertaken in patients in established labour. The results showed that the duration of bupivacaine was significantly longer than that of etidocaine, while the number of patients with good analgesia was equal in both groups. Motor blockade was less obvious in those patients receiving bupivacaine, but in neither group was this a finding of importance. At 5 minutes the Apgar scores of neonates from both groups were similar and any differences seen at 1 minute may be attributable to factors other than the drugs on trial.
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Acta Anaesthesiol Scand Suppl · Jan 1975
Comparative Study Clinical Trial Controlled Clinical TrialComparative study with etidocaine and bupivacaine in epidural block.
Etidocaine 1% and bupivacaine 0.5% (both with adrenaline 5 mug/ml) have been compared in a double blind study in epidural analgesia. Time of onset, duration, recession of analgesia and intensity as well as frequency of motor blockade were recorded in a selected group of patients undergoing varicose vein stripping. ⋯ Duration, recession and intensity of analgesia were similar for the two drugs. The main difference between them was that etidocaine produced a higher frequency and greater intensity of motor blockade.
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Acta Anaesthesiol Scand Suppl · Jan 1975
Comparative Study Clinical TrialIntercostal blocks with etidocaine. Preliminary report.
Although the results are few and should be considered as preliminary, the following conclusions may be drawn: 1. Etidocaine 0.5% and bupivacaine 0.5%, both with adrenaline (5 mug/ml), are comparable with regard to duration of sensory block. 2. ⋯ Adrenaline added to the solution counteracts the dilating effect. 4. Blood level studies of etidocaine do not at present show differences when 0.5% solution with or without adrenaline is used.
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Acta Anaesthesiol Scand Suppl · Jan 1975
Comparative Study Clinical Trial Controlled Clinical TrialA double-blind trial of bupivacaine and etidocaine in epidural block for surgical induction of labour.
Compared to bupivacaine, etidocaine has a quicker onset of action both in terms of initial analgesia and time taken to reach maximal extent of analgesia. ;owever, its duration of action is significantly shorter and it produces a striking degree of motor loss. These last two properties make etidocaine relatively unsuitable for obstetric practice, where a long duration of action and a reasonable mobility are desirable. However, it has been found useful for forceps delivery, because of the good muscle relaxation obtained and, because of its greater penetration, in abolishing the missed segments sometimes seen with bupivacaine.