AANA journal
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One of the very real complications possible in the use of local anesthetic agents is a relative overdose of the drug, resulting in an inordinate and potentially dangerous serum level. Even when using strict and careful technique, problems can occur. The reactions cited in the aforementioned cases were most likely the result of the accidental intravenous injection of a local anesthetic agent. ⋯ Nevertheless, local anesthetics are potentially toxic and their use should be approached with knowledge of and a healthy respect for their associated complications. It should also be remembered that virtually all local anesthetic toxic reactions are preventable and treatable. Their occurrence need not necessarily result in a poor outcome.