The New York state dental journal
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Peripheral ossifying fibroma (POF) and pyogenic granuloma (PG) belong to the group of "focal reactive overgrowths," having different histomorphologic representations. The pathogenesis of POF remains controversial. It has been observed that POF in some cases may initially develop as a PG that undergoes subsequent fibrous maturation and calcification. ⋯ The primary lesion was diagnosed as POF and the recurrent lesion as PG. The POF might have developed initially as PG and subsequent maturation led to the ossification of the lesion. These two lesions represent the progressive stages of the same spectrum of pathosis.