Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Apr 2021
Quality and methodology of clinical practice guidelines on antiviral pharmacotherapy for COVID-19 during the early phase of the pandemic.
Despite availability of reliable guidelines development methods, the risk of producing less reliable documents may be higher when the guidelines are developed rapidly. ⋯ Most guidelines or guidance documents published during the early phase of the COVID-19 pandemic were of poor quality, contained recommendations for the use of antiviral therapy for SARS-CoV-2 infection despite only very low quality of evidence available, and were not updated on a regular basis.
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The situation regarding COVID‑19 in Poland is rapidly evolving. Because of this, it is important to investigate COVID‑19 mortality and its predictors in one of the most densely populated regions of the country, Silesia Province. ⋯ The estimated in‑hospital fatality rate for COVID‑19 was 11.5%, which is lower than the average COVID‑19 fatality rate in other European countries. The risk of in‑hospital death was associated with sex, age, and the number of coexisting diseases, such as chronic cardiovascular and respiratory diseases.
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Pol. Arch. Med. Wewn. · Apr 2021
Paranasal sinus inflammatory changes in patients with ischemic stroke who underwent mechanical thrombectomy.
Chronic rhinosinusitis is one of the most widespread chronic diseases in the world, whereas stroke is the leading cause of death and disability. There are numerous reports on the relationship between chronic inflammatory diseases and cardio‑cerebrovascular diseases. ⋯ Moderate‑to‑severe inflammatory lesions indicating chronic rhinosinusitis are common in patients with stroke, which suggests the role of local inflammation in inducing acute cerebral ischemia.
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Pol. Arch. Med. Wewn. · Apr 2021
Risk assessments of chronic obstructive pulmonary disease using Bayesian network based on a provincial survey.
The diagnosis of chronic obstructive pulmonary disease (COPD) is based on spirometry tests that are difficult to perform in some populations. ⋯ The BN had a favorable performance in predicting COPD risks based on questionnaires. The risks associated with the combination of several risk factors should be noted.