Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Jan 2025
Ambient air pollution and risk of hospital admission due to acute and chronic coronary syndromes: a time-stratified case-crossover study in the 3 largest urban agglomerations in Poland.
Short-term exposure to air pollution may worsen the course of ischemic heart disease (IHD), causing acute and chronic coronary syndromes. ⋯ The exposure to PM10, PM2.5, and NO2 is associated with an increased short-term risk of hospital admission due to acute and chronic coronary syndromes.
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This article provides an overview of vitamin C for preventing and treating respiratory infections. Studies in a wide variety of animals have shown vitamin C to be protective against infections. In controlled trials in the general human population, >1 g/day vitamin C did not prevent common colds. ⋯ It is unlikely that vitamin C would reduce the risk of pneumonia in the general population, however, four trials reported a treatment benefit for pneumonia patients, although the findings encourage further research rather than providing firm evidence of efficacy. Vitamin C has been tested for COVID-19 and sepsis with conflicting results. Given the evidence that vitamin C reduces the severity and duration of the common cold, and the safety and low cost, it is not unreasonable for individuals to test whether 6-8 g/day is beneficial at the individual level.
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Pol. Arch. Med. Wewn. · Jan 2025
The role of lipoprotein(a) in atrial fibrillation: a systematic review.
Atrial fibrillation (AF) is the most prevalent form of cardiac arrhythmia worldwide. Early diagnosis and treatment are essential, emphasizing the need to develop novel biomarkers. Lipoprotein(a) [Lp(a)] has recently been widely investigated as a potential risk factor for various cardiovascular conditions, including AF. ⋯ Existing evidence suggests Lp(a) may play a pathophysiological role in AF patients, especially among patients who experience thromboembolic events. Nevertheless, this field requires further research due to inconsistencies in the existing evidence.
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Pol. Arch. Med. Wewn. · Jan 2025
Comparison of models predicting efficacy of radioiodine therapy in patients with differentiated thyroid cancer.
Differentiated thyroid cancer (DTC) is the most common type of endocrine malignancy, with rising incidence over recent decades. Despite a favorable prognosis, DTC management remains complex, often involving thyroidectomy followed by radioactive iodine (RAI) therapy. While RAI is crucial for patient outcomes, its efficacy varies, necessitating the identification of predictors for treatment response. ⋯ Our study underscores the utility of sTg as a single parameter for predicting RAI efficacy in DTC patients, with a defined cut-off value facilitating clinical decision-making. The inclusion of CLT status may further enhance predictive models. There is a need to advance personalized management approaches for DTC patients undergoing RAI therapy.