Polskie Archiwum Medycyny Wewnętrznej
-
Pol. Arch. Med. Wewn. · Sep 2021
Meta AnalysisImpact of continuous glucose monitoring on improving emotional well-being among adult people with type 1 diabetes mellitus: a systematic review and meta-analysis.
Real-time continuous glucose monitoring (CGM) has changed the way people with type 1 diabetes mellitus (T1DM) and health care providers perceive diabetes management and glucose control. ⋯ This is the first quantitative meta-analysis of studies involving adult patients exclusively with T1DM, providing further evidence for the ability of CGM systems to reduce fear of hypoglycemia and improve quality of life. Continuous glucose monitoring systems have advantage over SMBG in adults with T1DM and improve HbA1c levels.
-
Pol. Arch. Med. Wewn. · Sep 2021
Meta AnalysisOptimal duration of dual antiplatelet therapy followed by monotherapy in diabetic patients after percutaneous coronary intervention with drug‑eluting stent implantation: a Bayesian network meta-analysis.
The standard 12-month dual antiplatelet therapy (DAPT) following percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation that is recommended for the general population may not be suitable for patients with diabetes. ⋯ Short-term DAPT, as compared with extended-term therapy, was associated with a reduced primary endpoint in patients with diabetes after PCI with DES implantation.
-
Pol. Arch. Med. Wewn. · Sep 2021
Diagnostic agreement between radiofrequency echographic multispectrometry and dual-energy X-ray absorptiometry in the assessment of osteoporosis in a Polish group of patients.
Osteoporosis is still underdiagnosed in Poland, partly due to limited accessibility to the gold-standard diagnostic technique, that is, dual-energy X-ray absorptiometry (DXA) of the proximal femur and lumbar spine. The use of radiofrequency echographic multispectrometry (REMS) as an alternative diagnostic tool might be of particular interest because this technique is nonionizing, the devices are portable, and their utilization relatively cheap. ⋯ Radiofrequency echographic multispectrometry showed a significant diagnostic agreement with the corresponding DXA measurements. The study further confirms the usefulness of REMS in the assessment of osteoporosis.
-
Pol. Arch. Med. Wewn. · Sep 2021
Overhydration as a modifiable cardio-vascular risk factor in patients undergoing hemodialysis.
Introduction: Cardiovascular mortality in patients with end-stage renal disease (ESRD) remains high despite advances in dialysis techniques. This can be attributed to several traditional and nontraditional risk factors. Overhydration seems to be one of the promising cardiovascular risk factors that could be targeted to improve survival. Objectives: We aimed to assess the effect of chronic overhydration as well as changes in the degree of overhydration over time on cardiovascular and all-cause morbidity and mortality in patients undergoing hemodialysis. Patients and methods: We enrolled 511 patients with ESRD undergoing hemodialysis. ⋯ Cardiovascular toxicity of overhydration was reflected by elevated levels of N-terminal pro-B-type natriuretic peptide (P <0.001) and cardiac troponin T (P <0.001). Albumin and total cholesterol levels were the lowest in patients with severe overhydration (P <0.001). Mortality was lower in patients with normal hydration status and mild overhydration (P <0.001) as well as in those with stable low or descending overhydration pattern (P = 0.002). Conclusions: We showed that the degree of overhydration is significantly associated with the incidence of cardiovascular complications and prognosis in patients with ESRD undergoing hemodialysis.
-
Pol. Arch. Med. Wewn. · Sep 2021
Dehydroepiandrosterone sulfate indicates decreased sulfation capacity and impaired quality of life in patients with primary sclerosing cholangitis.
Impaired elimination of toxic compounds via inadequate sulfation may contribute to the pathogenesis of primary sclerosing cholangitis (PSC). Dehydroepiandrosterone (DHEA), which is metabolized into its sulfated form (DHEA-S) in the liver, has been linked with health-related quality of life (HRQoL) in various conditions. ⋯ Our findings support the role of impaired liver sulfation capacity in the development of PSC. Low levels of DHEA-S are associated with increased fatigue, a devastating symptom significantly affecting HRQoL. Thus, the effects of DHEA administration on chronic fatigue and other measures of HRQoL in patients with PSC warrant further attention.