Polskie Archiwum Medycyny Wewnętrznej
-
Pol. Arch. Med. Wewn. · Sep 2022
Differences in the predictors of left atrial appendage thrombus between men and women treated with dabigatran or rivaroxaban.
Some patients with atrial fibrillation (AF) develop left atrial appendage thrombus (LAAT) despite receiving anticoagulant treatment. Different scores were proposed to evaluate thromboembolic risk in patients with AF. Risk stratification according to sex is common in clinical practice. ⋯ The predictors of LAAT differ between men and women treated with dabigatran or rivaroxaban. In women, the CHA2DS2‑VASc‑RAF score had the highest predictive value, while in men all the scores had equally sufficient predictive value.
-
Pol. Arch. Med. Wewn. · Sep 2022
Recurrent cerebrovascular events in patients with history of cryptogenic stroke or transient ischemic attack and patent foramen ovale in long term follow-up.
Cryptogenic stroke may be associated with a patent foramen ovale (PFO). Both cardiovascular risk factors and transcatheter closure of PFO may have an impact on the risk of recurrent cerebrovascular events. ⋯ The occurrence of rCVE in the patients with cryptogenic stroke / TIA and PFO reached 4.3% regardless of a high percentage of patients who underwent the PFO closure. RoPE score was associated with a lower risk of rCVE in the study population.
-
Pol. Arch. Med. Wewn. · Sep 2022
Clinical characteristics and antiviral therapy in patients infected with hepatitis C virus in the interferon‑free era.
The highly effective and safe interferon (IFN)-free options were a breakthrough in the treatment of patients infected with hepatitis C virus (HCV). ⋯ The median age of HCV‑infected patients decreased over the years. They were less burdened with comorbidities and comedications, more likely to be treatment‑naïve, and had less advanced liver disease. The genotype‑specific regimens, predominantly used at the beginning of the IFN‑free era, were superseded by the pangenotypic regimens.