Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn.
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Pol. Arch. Med. Wewn. · Sep 2022
Clinical characteristics and antiviral therapy in patients infected with hepatitis C virus in the interferon‑free era.
The highly effective and safe interferon (IFN)-free options were a breakthrough in the treatment of patients infected with hepatitis C virus (HCV). ⋯ The median age of HCV‑infected patients decreased over the years. They were less burdened with comorbidities and comedications, more likely to be treatment‑naïve, and had less advanced liver disease. The genotype‑specific regimens, predominantly used at the beginning of the IFN‑free era, were superseded by the pangenotypic regimens.